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Известия вузов. Прикладная химия и биотехнология

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ИДЕНТИФИКАЦИЯ И ХАРАКТЕРИСТИКА ОСНОВНЫХ ВТОРИЧНЫХ МЕТАБОЛИТОВ ГРИБОВ FUSARIUMTRICINCTUM

https://doi.org/ 10.21285/2227-2925-2017-7-2-43-53

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Аннотация

Грибы рода Fusarium, паразитирующие на растениях, известны как продуценты разнообразных метаболитов с широкой биологической активностью. Метаболиты F. tricinctum ранее изучались на штаммах, изолированных преимущественно с пшеницы и кукурузы. Проведено исследование вторичных метаболитов F. tricinctum, изолированного из внутренних тканей побегов яблонь. Видовая принадлежность штамма подтверждена анализом последовательностей генов 18S рРНК. С помощью методов высокоэффективной жидкостной хроматографии (ВЭЖХ) обнаружено шесть вторичных метаболитов: энниатины (A, B, G, H), гибепирон B и ауреонитол. Идентификация данных соединений была проведена при помощи метода жидкостной хроматографии с масс-спектрометрическим детектированием (LC-MS). Выявлено, что неочищенный грибковый экстракт проявляет слабую антибактериальную активность в отношении Mycobacterium tuberculosis и Staphylococcus aureus.

Об авторах

Х. .. Мохамед
Саратовский государственный национальный исследовательский университет
Россия


А. М. Петерсон
Саратовский государственный национальный исследовательский университет
Россия


В. .. Ебрагем
Университет Генриха Гейне
Россия


П. .. Прокш
Университет Генриха Гейне
Россия


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Для цитирования:


Мохамед Х..., Петерсон А.М., Ебрагем В..., Прокш П... ИДЕНТИФИКАЦИЯ И ХАРАКТЕРИСТИКА ОСНОВНЫХ ВТОРИЧНЫХ МЕТАБОЛИТОВ ГРИБОВ FUSARIUMTRICINCTUM. Известия вузов. Прикладная химия и биотехнология. 2017;7(2):44-53. https://doi.org/ 10.21285/2227-2925-2017-7-2-43-53

For citation:


Mohamed H..., Peterson A.M., Ebrahimc W..., Proksch P... IDENTIFICATION AND CHARACTERIZATION OF MAJOR SECONDARY METABOLITES FROM THE FUNGUS FUSARIUM TRICINCTUM. Proceedings of Universities. Applied Chemistry and Biotechnology. 2017;7(2):44-53. (In Russ.) https://doi.org/ 10.21285/2227-2925-2017-7-2-43-53

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