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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vuzbiochemi</journal-id><journal-title-group><journal-title xml:lang="ru">Известия вузов. Прикладная химия и биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Proceedings of Universities. Applied Chemistry and Biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2227-2925</issn><issn pub-type="epub">2500-1558</issn><publisher><publisher-name>ИРНИТУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21285/achb.966</article-id><article-id custom-type="edn" pub-id-type="custom">ZCNHEA</article-id><article-id custom-type="elpub" pub-id-type="custom">vuzbiochemi-1421</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КРАТКИЕ СООБЩЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BRIEF COMMUNICATION</subject></subj-group></article-categories><title-group><article-title>Изучение антибиотикорезистентности молочнокислых бактерий Latilactobacillus sakei</article-title><trans-title-group xml:lang="en"><trans-title>Antibiotic resistance of Latilactobacillus sakei lactic acid bacteria</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3003-8638</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никифорова</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikiforova</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никифорова Анна Платоновна, к.т.н., доцент, доцент</p><p>197101, г. Санкт-Петербург, Кронверкский просп., 49а</p></bio><bio xml:lang="en"><p>Anna P. Nikiforova, Cand. Sci. (Engineering), Associate Professor, Associate Professor</p><p>49a, Kronverksky Ave., Saint Petersburg, 197101</p></bio><email xlink:type="simple">anna.p.nikiforova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5749-1459</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Позняковский</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Poznyakovsky</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Позняковский Валерий Михайлович, д.б.н., профессор, профессор, руководитель научно-образовательного центра «Прикладная биотехнология и нутрициология»</p><p>650056, г. Кемерово, ул. Ворошилова 22а</p></bio><bio xml:lang="en"><p>Valery M. Poznyakovsky, Dr. Sci. (Biology), Professor, Professor, Head of the Scientific and Educational Center “Applied Biotechnology and Nutrition”</p><p>22a, Voroshilov St., Kemerovo, 650056</p></bio><email xlink:type="simple">pvm1947@bk.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный исследовательский университет ИТМО</institution><country>Россия</country></aff><aff xml:lang="en"><institution>ITMO University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кемеровский государственный медицинский университет Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kemerovo State Medical University of the Ministry of Health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>07</day><month>04</month><year>2025</year></pub-date><volume>15</volume><issue>1</issue><fpage>137</fpage><lpage>142</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Никифорова А.П., Позняковский В.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Никифорова А.П., Позняковский В.М.</copyright-holder><copyright-holder xml:lang="en">Nikiforova A.P., Poznyakovsky V.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vuzbiochemi.elpub.ru/jour/article/view/1421">https://vuzbiochemi.elpub.ru/jour/article/view/1421</self-uri><abstract><p>Одной из наиболее серьезных проблем здравоохранения во всем мире является повышение устойчивости к антибиотикам. Следствием этой проблемы являются сложности при лечении некоторых заболеваний, рост смертности, увеличение медицинских расходов. Известно, что передача через пищевые цепи представляет собой один из важнейших путей распространения устойчивых к антибиотикам штаммов бактерий. По данным, представленным в российской и зарубежной литературе, молочнокислые бактерии могут служить резервуаром для передачи генов устойчивости к антибиотикам. В связи с этим важное значение имеет изучение антибиотикорезистентности штаммов молочнокислых бактерий, применяемых при производстве пищевых продуктов, особенно тех, которые не проходят термообработку перед употреблением в пищу. Целью проведенного исследования являлось изучение устойчивости к антибактериальным препаратам молочнокислых бактерий вида Latilactobacillus sakei. В работе было исследовано четыре штамма бактерий этого вида. Исследование было проведено с применением диско-диффузионного метода. Установлено, что изученные штаммы не обладали устойчивостью к большинству рассмотренных антибиотиков. Наименьшую устойчивость к антибиотикам показал штамм DSM 20017, который являлся чувствительным ко всем исследованным препаратам. Остальные изученные штаммы также продемонстрировали чувствительность к большинству препаратов, но показали промежуточную чувствительность к отдельным антибиотикам. Для более полной характеристики устойчивости молочнокислых бактерий вида Latilactobacillus sakei к антибиотикам требуется проведение дополнительных исследований, касающихся фенотипической устойчивости изучаемых штаммов.</p></abstract><trans-abstract xml:lang="en"><p>Antimicrobial resistance represents a serious threat to public health due to such negative consequences as the difficulty of treating certain diseases, higher mortality, and increased medical costs. Transmission through food chains is known to be one of the most important routes for the spread of antibiotic-resistant bacterial strains. According to scientific publications, lactic acid bacteria can serve as a reservoir for the transmission of antibiotic resistance genes. In this regard, it is important to study the antibiotic resistance of lactic acid bacteria strains used in food industry, particularly those not subjected to heat treatment prior to consumption. In this article, we investigate the resistance of Latilactobacillus sakei lactic acid bacteria to antibacterial preparations by a disk diffusion susceptibility test. The strains under study were not resistant to most of the antibiotics considered. The DSM 20017 strain, which was sensitive to all tested preparations, showed the least resistance to antibiotics. Other strains also demonstrated sensitivity to most of the studied antibacterial preparations, although with an intermediate sensitivity to certain antibiotics. Further research is required for a comprehensive characterization of the phenotypic resistance of Latilactobacillus sakei bacteria to antibiotics.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Latilactobacillus sakei</kwd><kwd>молочнокислые бактерии</kwd><kwd>антибиотики</kwd><kwd>пробиотики</kwd><kwd>антибиотикорезистентность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Latilactobacillus sakei</kwd><kwd>lactic acid bacteria</kwd><kwd>antibiotics</kwd><kwd>probiotics</kwd><kwd>antibiotic resistance</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bodke H., Jogdand S. Role of probiotics in human health // Cureus. 2022. Vol. 14, no. 11. P. e31313. DOI: 10.7759/cureus.31313.</mixed-citation><mixed-citation xml:lang="en">Bodke H., Jogdand S. Role of probiotics in human health. Cureus. 2022;14(11):e31313. 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