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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vuzbiochemi</journal-id><journal-title-group><journal-title xml:lang="ru">Известия вузов. Прикладная химия и биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Proceedings of Universities. Applied Chemistry and Biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2227-2925</issn><issn pub-type="epub">2500-1558</issn><publisher><publisher-name>ИРНИТУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21285/2227-2925-2019-9-2-239-249</article-id><article-id custom-type="elpub" pub-id-type="custom">vuzbiochemi-195</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФИЗИКО-ХИМИЧЕСКАЯ БИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PHYSICOCHEMICAL BIOLOGY</subject></subj-group></article-categories><title-group><article-title>Оптимизация условий экстракции биологически активных соединений с антиоксидантными свойствами из плодов боярышника (Crataegus)</article-title><trans-title-group xml:lang="en"><trans-title>Optimisation of conditions for extracting bioactive compounds exhibiting antioxidant properties from hawthorn fruit (Crataegus)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Валеева</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Valeeva</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>cтудентка кафедры технологии и организации общественного питания,</p><p>г. Самара</p></bio><bio xml:lang="en"><p>Student,</p><p>Samara</p></bio><email xlink:type="simple">426283802@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макарова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.х.н., заведующая кафедрой технологии и организации общественного питания,</p><p>г. Самара</p></bio><bio xml:lang="en"><p>Dr. Sci. (Chemistry), Head of Department of Technology and Organization of Public Catering,</p><p>Samara</p></bio><email xlink:type="simple">makarovanv1969@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Валиулина</surname><given-names>Д. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Valiulina</surname><given-names>D. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.т.н., доцент кафедры технологии и организации общественного питания,</p><p>г. Самара</p></bio><bio xml:lang="en"><p>Ph.D. (Engineering), Associate Professor, Department of Technology and Organization of Public Catering,</p><p>Samara</p></bio><email xlink:type="simple">dinara-bakieva@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Самарский государственный технический университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Samara State Technical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>28</day><month>09</month><year>2019</year></pub-date><volume>9</volume><issue>2</issue><fpage>239</fpage><lpage>249</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Валеева А.Р., Макарова Н.В., Валиулина Д.Ф., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Валеева А.Р., Макарова Н.В., Валиулина Д.Ф.</copyright-holder><copyright-holder xml:lang="en">Valeeva A.R., Makarova N.V., Valiulina D.F.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vuzbiochemi.elpub.ru/jour/article/view/195">https://vuzbiochemi.elpub.ru/jour/article/view/195</self-uri><abstract><p>Плоды боярышника являются традиционным лекарственным сырьем в народной медицине. В них содержатся важные органические кислоты и флавониды, которые способны восстанавливать сердечно-сосудистую систему организма: каротин, пектины, аскорбиновая кислота, сапонины и крахмал, а также витамины группы В. Основной формой использования лекарственного сырья являются экстракты. В данной работе использованы три технологии экстрагирования: традиционная – настаивание (37 °С, 2 ч), и инновационные – с использованием микроволнового (800 Вт, 1 мин) и ультразвукового облучения (0,5 Вт, 2 ч). С целью определения наиболее оптимального метода экстрагирования комплекса веществ с антиоксидантными свойствами из экстрактов плодов боярышника было изучено содержание сухих веществ, фенолов, флавоноидов, а также определена антиоксидантная активность с использованием двух методик: путем улавливания свободных радикалов и по методу FRAP (восстанавливающей силы). На основании результатов проведенных опытов можно заключить, что из всех рассмотренных технологий экстракции наиболее эффективной для плодов боярышника является экстракция с использованием ультразвукового излучения, поскольку по всем параметрам исследования были получены наибольшие показатели по сравнению с другими методиками экстрагирования: содержание фенолов составило 723 мг галловой кислоты/100 г; флавоноидов – 194 мг катехина/100 г; сухих веществ – 1,68%, а также антирадикальная активность составила 14,5 мг/см3 , восстанавливающая сила – 14,5 ммоль Fe2+/1 кг. Метод экстракции с использованием микроволнового облучения по полученным показателям не может быть рекомендован, так как уровень показателей ниже, чем в случае ультразвукового облучения и метода настаивания.</p></abstract><trans-abstract xml:lang="en"><p>Hawthorn berries are traditionally used as a medicinal raw material in folk medicine. This plant contains important organic acids and flavonoids, such as carotene, pectin, ascorbic acid, saponins, starch and group B vitamins, which are believed to facilitate the restoration of the cardiovascular system. Medicinal raw materials are primarily used in the form of extracts. In this work, we use three extraction technologies: one conventional technique, i.e. infusion (37 °С, 2 hours), and innovative ones involving the use of microwave (800 W, 1 min) and ultrasonic irradiation (0.5 W, 2 hours). In order to determine the most optimal method for obtaining a complex of substances exhibiting antioxidant properties from hawthorn fruit extracts, we studied the content of dry substances, phenols and flavonoids. In addition, the antioxidant activity was determined by trapping free radicals and using the FRAP method (restoring force). On the basis of the obtained experimental results, the hawthorn fruit extraction conducted using ultrasonic irradiation is found to be the most effective of all the considered technologies, since it yields the highest values for all the studied parameters as compared to other extraction methods. Thus, the following levels were achieved: phenols – 723 mg of gallic acid per 100 g; flavonoids – 194 mg of catechin per 100g; dry substances – 1.68 %; anti-radical activity – 14.5 mg/cm3 ; restoring force – 14.5 mmol of Fe2+ per 1 kg. Our results show that the extraction using microwave irradiation cannot be recommended, since the values obtained using this method are lower than those obtained by ultrasonic irradiation and infusion.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>плоды боярышника</kwd><kwd>экстрагирование</kwd><kwd>УЗИ</kwd><kwd>СВЧ</kwd><kwd>фенолы</kwd><kwd>флавоноиды</kwd><kwd>антирадикальная активность</kwd><kwd>восстанавливающая сила</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hawthorn fruit</kwd><kwd>extraction</kwd><kwd>ultrasonic</kwd><kwd>microwave</kwd><kwd>phenols</kwd><kwd>flavonoids</kwd><kwd>anti-radical activity</kwd><kwd>restoring force</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kashyap C.P., Arya V., Thakur N. Ethnomedicinal and phytopharmacological potential of Crataegus oxyacantha Linn. – A review // Asian Pacific Journal of Tropical Biomedicine. 2012. 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