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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">vuzbiochemi</journal-id><journal-title-group><journal-title xml:lang="ru">Известия вузов. Прикладная химия и биотехнология</journal-title><trans-title-group xml:lang="en"><trans-title>Proceedings of Universities. Applied Chemistry and Biotechnology</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2227-2925</issn><issn pub-type="epub">2500-1558</issn><publisher><publisher-name>ИРНИТУ</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21285/2227-2925-2019-9-3-447-460</article-id><article-id custom-type="elpub" pub-id-type="custom">vuzbiochemi-217</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ФИЗИКО-ХИМИЧЕСКАЯ И ОБЩАЯ БИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PHYSICOCHEMICAL AND GENERAL BIOLOGY</subject></subj-group></article-categories><title-group><article-title>Термопластическая экструзия в процессах пищевой биотехнологии</article-title><trans-title-group xml:lang="en"><trans-title>Thermoplastic extrusion in food biotechnology processes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шариков</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharikov</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.т.н., старший научный сотрудник,</p><p>г. Москва</p></bio><bio xml:lang="en"><p>Ph.D. (Engineering), Senior Researcher,</p><p>Moscow</p></bio><email xlink:type="simple">anton.sharikov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.т.н., заведующий отделом, </p><p>г. Москва</p></bio><bio xml:lang="en"><p>Ph.D. (Engineering), Head of the Department,</p><p>Moscow</p></bio><email xlink:type="simple">foodbiotech@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.т.н., ведущий научный сотрудник,</p><p>г. Москва</p></bio><bio xml:lang="en"><p>Ph.D. (Engineering), Leading Researcher,</p><p>Moscow</p></bio><email xlink:type="simple">ivanov.v.v@li.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Всероссийский научно-исследовательский институт пищевой биотехнологии – филиал «ФИЦ питания и биотехнологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Scientific Research Institute of Food Biotechnology, Federal Research Center of Food, Biotechnology and Food Safety</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>07</day><month>10</month><year>2019</year></pub-date><volume>9</volume><issue>3</issue><fpage>447</fpage><lpage>460</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шариков А.Ю., Степанов В.И., Иванов В.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Шариков А.Ю., Степанов В.И., Иванов В.В.</copyright-holder><copyright-holder xml:lang="en">Sharikov A.Y., Stepanov V.I., Ivanov V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://vuzbiochemi.elpub.ru/jour/article/view/217">https://vuzbiochemi.elpub.ru/jour/article/view/217</self-uri><abstract><p>Развитие пищевых биотехнологий предполагает совершенствование и оптимизацию всех стадий технологического процесса – от предобработки сырья до стадий биокатализа, ферментации и получения готового продукта. На основе релевантных научных источников проведен обзор перспектив интеграции в пищевые биотехнологические производства термопластической экструзии, имеющей ряд технологических и экономических преимуществ. Показано, что экструзия как стадия предподготовки сырья повышает степень его растворимости, дальнейшего гидролиза крахмала, белка, некрахмалистых полисахаридов с соответствующим ростом выхода продуктов биоконверсии. В технологии спирта использование экструдирования крахмалсодержащего сырья может стать фактором увеличения выхода этанола и снижения образования побочных метаболитов брожения, в пивоваренной – позволяет расширить применение несоложеных материалов при приготовлении сусла, при глубинном культивировании микроорганизмов (продуцентов ферментов) – повысить концентрацию среды и синтез ферментов. Приведены положительные результаты получения питательных сред на экструдированном сырье для микробиологического продуцирования L(+) молочной кислоты, производства заквасок и поликомпонентных сквашенных молокосодержащих продуктов. Совмещение экструзии и биокатализа в камере экструдера позволяет получать мальтодекстрины с дектрозным эквивалентом до 10 ед. Помимо переработки крахмалсодержащих субстратов экструзия в комплексе с биокаталитической обработкой обеспечивает глубокую модификацию биополимеров сырья с высоким содержанием белка и пищевых волокон, например, гидролиз обладающих антигенными свойствами термоустойчивых белковых фракций глицинина и β-конглицинина соевого шрота, повышение функциональности отрубей и содержания водорастворимых арабоксиланов в специализированных экструдированных продуктах. Основными факторами, влияющими на степень переработки сырья и качество целевых продуктов, являются влагосодержание и температура экструзии, дозировка ферментных препаратов. Описаны возможности совмещения процессов экструзии и биокатализа в одной системе реакторов или непосредственно в камере экструдера, что позволяет значительно повысить концентрацию перерабатываемых биотехнологических сред, упростить аппаратурно-технологический состав производственных линий, повысить их производственную мощность и эффективность использования энергоресурсов.</p></abstract><trans-abstract xml:lang="en"><p>The development of food biotechnology involves the improvement and optimisation of all stages of the technological process – from the pretreatment of raw materials to the stages of biocatalysis, fermentation and derivation of finished product. Based on relevant scientific sources, a review of the prospects for the integration of thermoplastic extrusion into food biotechnological production, which has a number of technological and economic advantages, is carried out. It is shown that extrusion as a stage of pre-treatment of raw materials increases the degree of solubility, allowing further hydrolysis of starch, protein and non-starch polysaccharides, with a corresponding increase in the yield of bioconversion products. In distillation processes, the use of extruded starch-containing raw materials can become a factor in increased ethanol yield and a reduction in the formation of minor metabolites of fermentation; in brewing, it allows the expanded use of unmalted materials in the preparation of wort; while, in the deep cultivation of microorganisms (enzyme producers), it can be a factor in the increased concentration of the medium and consequent synthesis of enzymes. Positive results for the derivation of nutrient media on extruded raw materials for microbiological production of L (+) lactic acid, production of starter cultures and multicomponent fermented milk-containing products are reported. A combination of extrusion and biocatalysis in the extruder chamber allows maltodextrins to be obtained having a dextrose equivalent of up to 10 units. In addition to the processing of starchy substrates by extrusion in combination with biocatalytic treatment, a deep modification of biopolymers materials having a high protein and dietary fibre content, for example, hydrolysis with heat-stable antigenic properties of the protein fractions of glycinin and conglycinin in soybean meal, increases the functionality of the bran content of water-soluble araboxylans in specialised extruded products. The main factors affecting the degree of processing of raw materials and the quality of the target products are moisture content and extrusion temperature, as well as dosage of enzyme preparations. The possibilities of combining the processes of extrusion and biocatalysis in one reactor system or directly in the extruder chamber are described. These can significantly increase the concentration of processed biotechnological media, simplify the hardware and process composition of production lines, at the same time as increasing production capacity and energy efficiency.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>экструзия</kwd><kwd>биотехнология</kwd><kwd>фермент</kwd><kwd>брожение</kwd><kwd>микроорганизм</kwd><kwd>высокая концентрация</kwd><kwd>биоэтанол</kwd></kwd-group><kwd-group xml:lang="en"><kwd>extrusion</kwd><kwd>biotechnology</kwd><kwd>enzyme</kwd><kwd>fermentation</kwd><kwd>microorganism</kwd><kwd>high concentration</kwd><kwd>bioethanol</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена за счет средств субсидии на выполнение государственного задания в рамках Программы Фундаментальных научных исследований государственных академий наук.</funding-statement><funding-statement xml:lang="en">This study was supported by grant of the Fundamental scientific research program of the Russian State Academies of Sciences.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Adekola K.A. 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