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STUDY OF STRUCTURE AND PROPERTIES OF THE TRIPLE POLYMER-METAL COMPLEX CHITOSAN-Cu(II)-POLYHEXAMETHYLENEGUANIDINE

https://doi.org/ 10.21285/2227-2925-2017-7-1-31-38

Abstract

The method of synthesis has been developed and the structure of the triple polymer-metal complex based on chitosan, polyhexamethyleneguanidine hydrochloride and Cu (II) ions have been studied. The desired pH of the medium and the component ratio for stoichiometric complex are ascertained. The coordination sphere of the complex was shown to form by amine groups of polymeric ligands and hydroxyl groups. The estimation of the antibacterial properties of the synthesized complex against Gram-positive and Gram-negative sanitary-indicative bacteria is discussed.

About the Authors

V. A. Dobysh
Institute of Chemistry of New Materials of National Academy of Sciences of Belarus
Russian Federation


N. V. Koktysh
Institute of Chemistry of New Materials of National Academy of Sciences of Belarus
Russian Federation


N. A. Belyasova
Belarusian State Technological University
Russian Federation


V. V. Kornei
Institute of Chemistry of New Materials of National Academy of Sciences of Belarus
Russian Federation


References

1. Тарасевич В.А., Макатун В.Н., Белясова Н.А., Антоновская Л.И., Добыш В.А. Синтез и биоцидные свойства производных полигексаметиленгуанидина // Известия НАН Беларуси. Сер. хим. наук. 2010. № 3. С. 79-84.

2. Dobysh V.A. Koktysh N.V., Tarasevich V.A., Agabekov V.E., Makatun V.N., Antonovskaya L.I., Belyasova N.A. Synthesis and study of properties of the polyhexamethyleneguanidine complexes with the ions Cu2+, Zn2+, and Ni2+ // Russian Journal of General Chemistry. 2012. Vol. 82, № 11. P. 1764-1769. DOI: 10.1134/S1070363212110035

3. Хитин и хитозан: Получение, свойства и применение / Под. ред. К.Г. Скрябина, Г.А. Вихоревой, В.П. Варламова. М.: Наука, 2002. 368 с.

4. Kramareva N.V., Finashina A.V., Kucherov A.V., Kustov L.M. Copper complexes stabilized by chitosans: peculiarities of the structure, redox, and catalytic properties // Kinetics and Catalysis. 2003. Vol. 44, № 6. P. 793-800. DOI: 10. 1023/B: KICA.0000009056.74699.b8

5. Низельский Ю.Н., Козак Н.В., Рябов С.В., Кобылинский С.М., Керча Ю.Ю. Строение бактерицидоактивных комплексов меди (2+) на поверхности хитозана: материалы Восьмой международной конф. «Современные перспективы в исследовании хитина и хитозана». М., 2006. С. 114-118.

6. Добыш В.А., Курман П.В., Шабуня П.С., Коктыш Н.В., Тарасевич В.А., Агабеков В.Е., Макатун В.Н., Белясова Н.А. Влияние молекулярно-массовых и структурных характеристик полигексаметиленгуанидина на его биоцидную активность // Журнал общей химии. 2012. Т. 82, N 10. С. 1690-1694.

7. Белясова Н.А., Антоновская Л.И., Михайловский И.С., Самойлов М.В., Мельникова Г.Б., Тарасевич В.А., Добыш В.А. Получение и антимикробные свойства дисперсных форм липидов и полигексаметиленгуанидина // Известия НАН Беларуси. Сер. биол. наук. 2014. N 3. С. 66-69.

8. Rhazi М., Desbrieres J., Tolaimate A., Rinaudo M., Vottero P., Alagui A. Contribution to the study of the complexation of copper by chitosan and oligomers // Polymer. 2002. Vol. 43. P. 1267-1276. DOI: 10.1016/S0032-3861(01) 00685-1

9. Zhang Y., Jiang J., Chen Y. Synthesis and antimicrobial activity of polymeric guanidine and biguanidine salts // Polymer. 1999. Vol. 40. P. 6189-6198. DOI: 10.1016/S0032-3861(98)-00828-3

10. Monteiro О., Airoldi С. Some thermodynamic data on copper-chitin and copper-chitosan biopolymer interactions // Journal of Colloid and Interface Science. 1999. Vol. 212. P. 212-219. DOI: 10.1006/jcis.1998.6063

11. Rosthauser J.W., Winston A. Crosslinking of hydroxamic acid copolymers through iron chelation // Macromolecules. 1981. Vol. 14. P. 538-543. DOI: 10.1021/ma50004a015


Review

For citations:


Dobysh V.A., Koktysh N.V., Belyasova N.A., Kornei V.V. STUDY OF STRUCTURE AND PROPERTIES OF THE TRIPLE POLYMER-METAL COMPLEX CHITOSAN-Cu(II)-POLYHEXAMETHYLENEGUANIDINE. Proceedings of Universities. Applied Chemistry and Biotechnology. 2017;7(1):31-38. (In Russ.) https://doi.org/ 10.21285/2227-2925-2017-7-1-31-38

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ISSN 2227-2925 (Print)
ISSN 2500-1558 (Online)